Thursday, 1 March 2007

Pleural mesothelioma (Respiratory Medicine)

An overview of pleural pleural mesothelioma tumor is from the visceral and parietal mediastinum or pleural tumors diaphragmatic four parts. Incidence rate higher than abroad, and 0.04% for 0.07~0.11%. Less than 1% of all cancer mortality worldwide. In recent years, there is a rising trend. More prevalent 50 years old, male to female ratio was 2:1. With asbestos exposure. Currently, there is no effective treatment for malignant type. Clinical manifestations 1. Limitations can only no obvious discomfort or chest pain, shortness of breath after. 2. Have more diffuse severe chest pain, shortness of breath, and so skinny. 3. 側 thoracic limitation full spontaneous delivery voiced breathing sounded reduce or disappear. 4. Have axillary lymph nodes and the supraclavicular fossa.1 diagnosis. Chest pain, shortness of breath, wasting and other symptoms. 2. Pleural effusion, and pleural thickening signs. 3. See pleural nodules in chest CT or chest. 4. Thoracoscopy shows nodules can be removed through the Organization of diagnostic activities. Treatment principles should be the first choice of treatment for localized and can diffuse combining surgery and chemotherapy. Medicine Principles 1. Transcranial links with a chest pain, indomethacin, ampules and other painkillers. 2. ADM is effective drug treatment of the disease, with more than cisplatin, mitomycin, cyclophosphamide, joint use of MTX. 3. IFN-γ, IL-as a complementary therapy. 4. Pleural effusion who will be talcum powder, such as tetracycline pleurodesis.Auxiliary chest and hydrothorax-based disease screening and inspection checks. Chest CT possible conditional admission or segmentation thoracoscopic biopsy can be diagnosed. Evaluation 1. Cure : Symptoms, signs disappeared, the disappearance of mesothelioma or surgical excision. 2. : Improved symptoms, signs have improved significantly reduce pleural effusion, mesothelioma narrow. 3. Healed : symptoms, no signs of improvement, pleural effusion increased speed, increased tumor. Experts suggest pleural mesothelioma often associated with asbestos exposure, therefore, the attention of labor protection. reduce or avoid contact with asbestos is an effective measure to prevent the disease. Limitations were more benign and effective treatment; Even diffuse malignant, Adriamycin chemotherapy used to be achieved positive results can significantly prolong survival.

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